Actemra Injection

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Actemra Injection is a prescription medicine called an Interleukin-6 (IL-6) receptor antagonist. ACTEMRA is used to treat: Adults with moderately to severely active rheumatoid arthritis (RA), after at least one other medicine called a Disease-Modifying Anti Rheumatic Drug (DMARD) has been used and did not work well. Adults with giant cell arteritis (GCA). People with active PJIA ages 2 and above. People with active SJIA ages 2 and above People age 2 years and above who experience severe or life threatening Cytokine Release Syndrome (CRS) following chimeric antigen receptor (CAR) T cell treatment.

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ACTEMRA is not approved for subcutaneous use in people with CRS. It is not known if ACTEMRA is safe and effective in children with PJIA, SJIA, or CRS under 2 years of age or in children with conditions other than PJIA, SJIA or CRS. Hepatitis B infection in people who carry the virus in their blood. If you are a carrier of the hepatitis B virus (a virus that affects the liver), the virus may become active while you use ACTEMRA. Your healthcare provider may do blood tests before you start treatment with ACTEMRA and while you are using ACTEMRA. Tell your healthcare provider if you have any of the following symptoms of a possible hepatitis B infection.

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Indicated for adults with moderate-to-severe active rheumatoid arthritis with inadequate response to 1 or more disease modifying antirheumatic drugs (DMARDs) May use alone or in combination with methotrexate or other DMARDs Serious Allergic Reactions. Serious allergic reactions, including death, can happen with ACTEMRA. These reactions can happen with any infusion or injection of ACTEMRA, even if they did not occur with an earlier infusion or injection. Tell your healthcare provider before your next dose if you had hives, rash or flushing after your injection. Seek medical attention right away if you have any of the following signs of a serious allergic reaction: