Lorcaserin Is Now Available In Pakistan
Lorcaserin (generic name) is available by the brand name of Belviq and Belviq-XR. It is a serotonin receptor agonist (5 HT 2C). It acts on the neuronal receptors present in the hypothalamus that is responsible for satiety.
Other drugs (fenfluramine and dexfenfluramine) also act on these receptors, however, since these drugs are non-selective, they are associated with more adverse events. It is used in obese adults with a Body mass index (BMI) of 30 kg//m² or more for weight loss as an adjunct to diet and exercise. It is also used for weight loss in adults with a BMI of 27 kg/m² or more and at least one weight-related comorbid condition such as diabetes mellitus, dyslipidemia, and hypertension.
belviq become fda-permitted to be used in adults with a bmi of 30 and over, or for human beings who’ve a body mass index of as a minimum 27 and have at least one weight-associated situation such as high blood pressure, type 2 diabetes, or high ldl cholesterol.
prescribing facts for belviq explains that users take one 10 milligram tablet twice every day in conjunction with a low-calorie food regimen and workout application. in line with the fda, the drug need to be taken for the relaxation of the affected person’s lifestyles to preserve a healthful weight. belviq must no longer be taken by way of girls who are pregnant or breastfeeding.1?
in medical trials, researchers studied 8000 obese and obese patients. the average amount of weight misplaced among those take a look at topics become 3 to 3.7% of their total body weight. roughly forty seven% of patients with out diabetes lost as a minimum 5% in their general body weight, as compared with 23% of sufferers who took a placebo.2?
initial research display that lorcaserin is secure when taken at the encouraged dosage of 10 mg twice every day. due to the fact serotonin agonists along with lorcaserin can motive serotonin syndrome, the manufacturer recommends that patients taking other serotonergic pills inclusive of antidepressants avoid coadministration of lorcaserin. valvulopathy, a risk with preceding weight loss pills, has no longer been established with lorcaserin; but, the drugs has no longer been evaluated in sufferers with massive valvulopathy or congestive heart failure. its lengthy-term effects are unclear as it has not been studied for a duration longer than years.